How a genetic split helped plants conquer polluted soils
Phytochelatin synthases (PCSs) produce phytochelatins—tiny, cysteine-rich peptides that bind and neutralize toxic metal ions such as cadmium and arsenic. These molecules act as the plant’s natural detox system, sequestering harmful elements into vacuoles to prevent cellular damage. ⌘ Read more
Rapid amyloid-β clearance and cognitive recovery by modulating BBB transport
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Poland votes to ban fur farming by 2033, with payouts for early closures ⌘ Read more
Bravo went to cat heaven today. ⌘ Read more
If you could redesign Linux userland from scratch, what would you do differently?
If we kept Linux the kernel exactly as it is today, but redesigned everything in userland from scratch (the init system, the filesystem hierarchy, the shell, libc, packaging, configuration, dbus, polkit, PAM, etc.), what would you do differently, and why? ⌘ Read more
Game over. AGI is not imminent, and LLMs are not the royal road to getting there
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Work begins to restore power to Ukraine’s Zaporizhzhia nuclear power plant ⌘ Read more
IDEs we had 30 years ago and lost (2023)
Article URL: https://blogsystem5.substack.com/p/the-ides-we-had-30-years-ago-and
Comments URL: https://news.ycombinator.com/item?id=45626910
Points: 500
# Comments: 446 ⌘ Read more
My cat being the diva that she is ⌘ Read more
Polish judge refuses to extradite Nord Stream blasts suspect over ‘just act’ ⌘ Read more
It’s soft and warm here, unlike on the streets. I stayz. ⌘ Read more
The face this kitten made ⌘ Read more
Satellite images confirm 11 fuel tanks destroyed at Crimean oil terminal after Ukrainian strikes ⌘ Read more
Trump’s Zelensky meeting confirms one thing: Putin is leading negotiations ⌘ Read more
Researchers’ autonomous system makes it easier to transport cargo on the moon
Autonomy algorithms developed by researchers at the University of Toronto Institute for Aerospace Studies (UTIAS) could one day make cargo transport on the moon safer and more efficient for astronauts. ⌘ Read more
Scaling Postgres to the next level at OpenAI
TIL OpenAI uses (used?) one primary write instance for their PostgreSQL cluster with dozens of read replicas. This powers the core ChatGPT service which has hundreds of millions of users and, needless to say, is a critical backbone to it.
The talk implies they shard now, but the whole video emphasises all the optimizations they did in order to support their workload through a single primary. It isn’t mentioned at what time they switched to sharding, but it’s heavily implied that … ⌘ Read more
ICE tickets Chicago man with legal residency $130 for not having his papers on him: ‘It’s not fair…I’m a resident’
Gregory Royal Pratt,  Reporter -  Chicago Tribune
_Stephan: Do you always have your papers on your person? If you immigrated from another country, even if you are a White person, it might be a good idea to do so. Like everything else dictator Trump is doing, having his Gestapo stop people and demanding t … ⌘ Read more
US Seizes 15B BTC, Indicts Chairman: Forced Labor Scam Compounds, Crypto Fraud
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Trump Could Soon Make America’s Refugee Program a Tool for White Nationalism
Noal Lanard,  Reporter -  Mother Jones
_Stephan: Yet another story about the growing White supremacy racism of dictator Trump, who has always been a racist, his administration, and the Republican Party. Soon, we are going to see whether the fascist majority of the Supreme Court eliminates the Voting Rights Act. The United States has rejected 160 years of its history since … ⌘ Read more
Trump urges Zelensky to talk peace with Putin, cools on sending Tomahawks ⌘ Read more
‘Finances are getting tighter’: US car repossessions surge as more Americans default on auto loans
Edward Helmore,  Reporter -  The Guardian (U.K.)
_Stephan: You don’t hear much about the auto loan business, but I, and economists who study this, when something fundamental changes in a negative way, see it as a canary warning us about the state of the American economy. And it is getting harder and harder to work out what is actua … ⌘ Read more
Something Weird Is Happening to Earth’s Magnetic Field
Passant Rabie,  Science Reporter -  Gizmodo
Stephan: It isn’t clear to even scientists exactly what this change in Earth’s magnetic field is going to cause, but clearly it will be something dramatic.
_Swarm is a constellation of Earth observing satellites to unlock the mysteries of the planet’s geomagnetic force. … ⌘ Read moreUkraine Sinks New Russian Sea Drone in First-Ever Naval Intercept Near Black Sea Trade Routes ⌘ Read more
Just bought a new toilet brush, it looks a bit different to the box. Do I return it? ⌘ Read more
Russia loses 1,150 soldiers over past day ⌘ Read more
Took care a pregnant feral cat, and now she brings her kittens to my desk.. ⌘ Read more
Rashid Khan reacts to late-night attack on civilians: ‘Absolutely immoral and barbaric…must not go unnoticed’ ⌘ Read more
Chinese Nobel Prize-winning physicist Chen Ning Yang dies at 103
Chinese Nobel Prize-winning physicist Chen Ning Yang, one of the most influential scientists in modern physics, died in Beijing on Saturday. He was 103. ⌘ Read more
Little man is 16. He is the chillest, most loving dude. Super undignified, but he could not care less. ⌘ Read more
Trump Says Putin Should Be Allowed To Keep The Land He Has Seized In Ukraine ⌘ Read more
Hello World ⌘ Read more