Unlocking cell identity: RNA sequestration in P-bodies directs cell fate transitions
A new study published in Nature Biotechnology shows that stem cell differentiation is linked to cellular structures called P-bodies, providing a potential means of controlling cell identity. Researchers at Baylor College of Medicine, the University of Colorado Boulder and collaborating institutions studied P-bodies in various developmental stages across multiple vertebrate species and found that selective RNA seques … ⌘ Read more

Bending biogenic crystals naturally without external forces
From creating flexible gadgets to better medicines, the art of bending crystals is reshaping technology and health, and at the University of Houston a crystals expert makes it look almost like a magic trick. ⌘ Read more

China’s rising meat demand drives Brazilian soybean farming and resource use
Behind a steak served in China, there is often a soybean cultivation in Brazil. A new study, published in Nature Food, presents a snapshot of an increasingly interconnected and fragile food system. ⌘ Read more

How a genetic split helped plants conquer polluted soils
Phytochelatin synthases (PCSs) produce phytochelatins—tiny, cysteine-rich peptides that bind and neutralize toxic metal ions such as cadmium and arsenic. These molecules act as the plant’s natural detox system, sequestering harmful elements into vacuoles to prevent cellular damage. ⌘ Read more

Rapid amyloid-β clearance and cognitive recovery by modulating BBB transport
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Epigenetic changes help cells adapt to low oxygen levels, study reveals
Researchers at Karolinska Institutet have discovered how cells can adjust their gene activity to survive when oxygen runs low. The study, published in Nature Cell Biology, reveals that cells use a previously unknown mechanism to control which proteins are produced—and how quickly. ⌘ Read more

Exploring the power of plants to make drugs out of sunlight
Plants are consummate chemists, using the sun’s energy and carbon dioxide from the air, to conjure a dazzling array of complex natural products in ways that cannot be replicated synthetically in the lab. ⌘ Read more

Ten Bizarre Creatures from Beneath the Waves
Our oceans and seas are a hotbed of weird and wonderful nature, home to some of the most remarkable species known to science. In these extreme ecosystems, bizarre creatures thrive and perform feats that scientists once thought were impossible. In this list, we plunge beneath the waves to explore some of the most surprising life […]

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Addictive-like behavioural traits in pet dogs with extreme motivation for toys
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DNA repair mechanisms help explain why naked mole-rats live a long life
Naked mole-rats are one of nature’s most extraordinary creatures. These burrowing rodents can live for up to 37 years, around ten times longer than relatives of a similar size. But what is the secret to their extreme longevity? How are they able to delay the decay and decline that befalls other rodents? The answer, at least in part, is due to a switch in a common protein that boosts DNA repair, according to new research published i … ⌘ Read more

Dijkstra on the foolishness of natural language programming (1978)
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DNA repair mechanisms help explain why naked mole-rats live a long life
Naked mole-rats are one of nature’s most extraordinary creatures. These burrowing rodents can live for up to 37 years, around ten times longer than relatives of a similar size. But what is the secret to their extreme longevity? How are they able to delay the decay and decline that befalls other rodents? The answer, at least in part, is due to a switch in a common protein that boosts DNA repair, according to new research published i … ⌘ Read more

Physicists are uncovering when nature’s strongest force falters
The strong nuclear force may abruptly loosen its grip on the fundamental particles that make up matter at a special “critical point” – researchers are now getting a clearer picture of when that point is reached ⌘ Read more

Destined to melt: Study warns glaciers’ ability to cool surrounding air faces imminent decline
Glaciers are fighting back against climate change by cooling the air that touches their surfaces. But for how long? The Pellicciotti group at the Institute of Science and Technology Austria (ISTA) has compiled and re-analyzed an unprecedented dataset of on-glacier observations worldwide. Their findings, published today in Nature Climate Change, demonstrate that glaciers will likely reach the peak of their … ⌘ Read more

How nature can make urban dwellers healthier
A study by Rutgers ecologist Myla Aronson and colleagues has found “overwhelming” evidence that increasing biodiversity in cities—establishing parks, installing native plants and encouraging sustainable landscaping—can significantly improve human health. ⌘ Read more

Top nature group to unveil new ‘red list’ of threatened species
The world’s top conservation body is holding its world congress starting Thursday in the Emirati capital Abu Dhabi and will unveil its updated “red list” of threatened species. ⌘ Read more

Natural barriers in northern Sweden’s rivers challenge downstream assumptions
Rivers in northern Sweden do not always become wider or richer in species further downstream. Natural barriers shape the flow and stop plants from spreading, new research from Umeå University shows. The study is published in the journal Communications Earth & Environment. ⌘ Read more

@movq@www.uninformativ.de LOL. I wish and hope they keep proposing it until the proposers die of natural causes, and then it vanishes. Hopeful thinking, I know…

I stopped especially for this photo during a relaxed after-work tour today. I don’t know if I’ve mentioned it before, but the nature here with the park, forest, and lakes is really beautiful and always lifts my mood! ⌘ Read more

@alexonit@twtxt.alessandrocutolo.it Personally, I find the reversed order of URL first and then timestamp more natural to reference something. Granted, URL last would be kinda consistent with the mention format. However, the timestamp doesn’t act as a link text or display text like in a mention, so, it’s some different in my opinion. But yeah.

** Strata **

A Counterfeit - a Plated Person -

I would not be -

Whatever strata of Iniquity

My Nature underlie -

Truth is good Health - and Safety, and the Sky.

How meagre, what an Exile - is a Lie,

And Vocal - when we die -

– Emily Dickinson

I made another game! This one pretty much has one single verb:“move.” The game, like most games I make, is a roguelike that relies heavily on probabilities and rng (random number generation).

Each level is … ⌘ Read more

@movq@www.uninformativ.de Holy shit, that’s insane! :-D I tried it, but i’m absolutely terrible at these type of games. I’m having trouble with the keys to move around. Maybe after ages I would pick it up and it becomes natural. I just was never a real gamer.

I will definitely try to read through the code, though! This looks sick. 8-)

@movq@www.uninformativ.de Oh, nice read!

If I’m in the woods, I’d like to not waste my time with computers and focus on the beauty of nature. ;-) So, I’m not gonna participate in that event. But I’d read your articles on that subject anytime. :-)

Distrobox is pretty handy and kind of amazed I haven’t played with it before now. I wanted to quickly try out Proton’s Authenticator they just released, but they only had binaries for Ubuntu and Fedora (naturally), but I’m on Void Linux on this laptop.

Installed the latest basic Fedora image with Distrobox, used dnf to install the downloaded rpm file within it, and presto, running the app within Void like I’d just downloaded it though the normal repos.

A mate visted me and we went on a few hours long hike. We came across a mythical creature in its natural habitat:

https://lyse.isobeef.org/waldspaziergang-2025-07-12/

@bender@twtxt.net Both Gopher and Mastodon are a way for me to “babble”. 😅 I basically shut down Gopher in favor of Mastodon/Fedi last year. But the Fediverse doesn’t really work for me. It’s too focused on people (I prefer topics) and I dislike the addictive nature of likes and boosts (I’m not disciplined enough to ignore them). Self-hosting some Fedi thing is also out of the question (the minimalistic daemons don’t really support following hashtags, which is a must-have for me).

I’ll probably keep reading Fedi stuff, I just won’t post that much, I think.

Enjoying nature and walking through this green and calm scenery. 🌳🚶‍♂️🌳 ⌘ Read more

Enjoying nature and walking through this green and calm scenery. 🌳🚶‍♂️🌳 ⌘ Read more

10 Recent Times the Earth Acted Bafflingly Strange
We like to think Earth is a well-oiled planetary machine—spinning reliably, shifting gradually, and following natural rhythms. But every now and then, it throws us a curveball. From pulsating seismic events to disappearing landmasses and bizarre atmospheric phenomena, these recent examples prove that our planet still has secrets. Whether explained after the fact or still […]

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photo evidence of why cat people are naturally gravitated towards vim motions ⌘ Read more

10 Perilous Hikes Still Open to the Public Today
These ten trails span the globe, from Asia’s sacred peaks to North America’s desert labyrinths, each offering a unique blend of natural beauty, cultural resonance, and heart-stopping exposure. Whether it’s the vertiginous boardwalks of China, the engineered marvels of Spain, or the secluded canyons of Utah, every hike demands respect for both terrain and tradition. […]

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Russia Forces 20,000 Naturalized Migrants to Fight in Ukraine or Face Losing Citizenship ⌘ Read more

AlphaEvolve: A Gemini-powered coding agent for designing advanced algorithms
See also https://www.nature.com/articles/d41586-025-01523-z ( https://archive.is/NBaXE)

Comments URL: https://news.ycombinator.com/item?id=43985489

Points: 501

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The effect of ChatGPT on students’ learning performance
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10 Individuals Allegedly Killed by the U.S. Government
Throughout American history, certain tragic and untimely deaths have sparked deep suspicion, skepticism, and public intrigue. Official narratives often point to suicide, accidents, or random violence—but the shadowy nature of these incidents frequently leads many to question if something more sinister might be at play. From whistleblowers and journalists to political insiders and controversial figures, […]

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10 Disc Jockeys Who Barricaded Themselves in the Studio
A disc jockey is in charge of playing music for a specific audience on the radio, and it is also their job to entertain that audience. Some disc jockeys have a natural ability to keep listeners’ attention, but sometimes, it takes a clever stunt to engage the crowd. One popular stunt performed by DJs involves […]

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10 Sci-Fi & Fantasy Films That Are Actually About Climate Change
It’s second nature for any filmmaker worth their salt to pack their movies with themes that contextualize and expand upon the action on screen. Still, humble viewers that we are, many of us ignore the subtext and latch onto the explosions, fights, and romantic flings instead. So, it pays to go back and take another […]

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Yesterday, before our second (and last) move today, I took the opportunity to take a relaxing ride on my bike along my running route from some years ago and enjoy the nature. ⌘ Read more

10 Conceptions of What Extraterrestrial Could Look Like
The demands of everyday life, in the form of natural stimuli, prompt the development of the various behavioral traits and physical structures of plants and animals. In trying to envision the appearance of extraterrestrial beings, scientists once turned to Earth’s fossil record. After all, it provided evidence as to how organisms had already evolved on […]

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@eapl.me@eapl.me I wouldn’t call it natural, it is the way Bluesky decided to handle handles (not meaning to make a pun, or anything). There is no other way, but that.

The bottomline is, there are agreed upon “standards”, right? From example, on Yarnd you show as “eapl.me”, from “eapl.me”. A kind of weird redundancy because on twtxt, ever since I started using it, one will expect to see a “nick” (equivalent to a person’s first name), from “a domain” (like a surname).

There is nothing holding back someone from giving themselves the nick:

thisismyawesomenickforwhichiwillbeknownforeverandeveritsgreatisntit

But, do we really want that? 😅

10 Pop Culture Figures Who Actually Existed
From Darth Vader to Mary Poppins, pop culture icons can excite, enrage, or inspire us. And though most characters tend to be wholly fictional in nature, some famous ones are actually based on real-life people. Here’s our list of 10 pop culture figures who existed IRL. Related: Top 10 Underrated Minor Characters from Pop Culture […]

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Act natural… maybe they’ll think it’s a yoga pose ⌘ Read more

10 Times Humanity Tried to Redesign the Calendar
For most of us, the Gregorian calendar is simply the way time works. But history is filled with people and cultures who believed they could build something more rational, accurate, or aligned with nature or ideology. Some were utopian dreams, others were bureaucratic rethinks—but all of them tried to challenge what we now take for […]

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Ten Animals with More Interesting Sex Lives Than You
The animal kingdom is full of weird and wonderful creatures having weird and wonderful sex. After all, reproduction is one of the core processes of life. So why not do it in style? Perilous journeys to find a partner. Elaborate mating rituals. Shocking acts of passion and lust. Nature has it all. From self-pleasuring monkeys […]

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How to Run DeepSeek LLM Locally on Mac
If you follow AI news, or even tech news, you might have heard of DeepSeek by now, the powerful Chinese Large Language Model that has capabilities rivaling ChatGPT while having dramatically lower training costs. DeepSeek is designed for advanced reasoning, with general purpose natural language and ChatBot abilities, task competency, research, while also being excellent … Read More ⌘ Read more

Components vs. Containers: Fight?
WebAssembly components offer a new way to deploy microservices and other applications in cloud native environments. This naturally raises the question: is the upstart component out to replace containers? Or is this one of those situations… ⌘ Read more

@lyse@lyse.isobeef.org This is so crazy to me. When I think “forest”, I assume “untouched nature”, but that couldn’t be further from the truth. 🫤

Ten Animal Bodily Fluids and Their Extraordinary Uses
From nourishing worm milk to poisonous moth ooze, the animal kingdom is home to all kinds of hidden marvels, and animal secretions are no exception. Nature is brimming with astonishing juices. The fluids take on various roles that leave some bowled over in wonder, while others feel a little nauseous. Here are ten of the […]

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10 Crazy Ideas for Colonizing Outer Space
Are we humans destined for outer space? It would seem so. Because eventually, what’s a civilization to do other than expand to other worlds beyond its own comfortable cosmic nursery? Whether based on science fiction or science-science, as civilization advances, it seems that the natural inkling is to explore and expand, to settle its solar […]

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10 Severe Medical Conditions with Surprising Health Benefits
Throughout human evolution, genetic variations that cause devastating diseases have persisted in populations at rates that seem to defy natural selection. This genetic paradox has prompted scientists to investigate why traits that cause serious illness in some individuals remain so common. Research has revealed a fascinating pattern: Many severe medical conditions offer unexpected health advantages […]

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