‘Switchbody’ turns enzyme activity on with antibody–antigen binding
By fusing enzyme fragments to antibodies, researchers from the Institute of Science Tokyo, in Japan, developed an innovative enzyme switch called “Switchbody,” which is activated when bound to its target antigen. Switchbody is based on a trap-and-release of enzyme fragment that dynamically controls enzyme activity, offering new opportunities in diagnostics, therapeutics, and precision bioprocessing. ⌘ Read more